Using Micronization to Reduce API Particle Size ...
Jan 16, 2013· A bead mill uses wet mechanical milling to obtain nanoscale particles as small as 200–400 nm in what can be called micronization, or perhaps more accurately named "nanonization" because it refers to nanometer scale, says Smith. In an agitator bead mill, grinding beads and agitating elements are used to reduce the API particle size through ...